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OptiGel® Mini Technology

INNOVATIVE ORAL SOFTGEL PLATFORM THAT DELIVERS FULL STRENGTH APIS IN A SMALL, POWERFUL SOFTGEL

As the leading innovator of softgel technology, Catalent has developed the next generation in softgels that deliver full strength efficacy in a smaller capsule size more preferred by patients and consumers.



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TECHNICAL ADVANTAGES

  • Enables higher API concentrations in smaller capsules
  • Helps improve absorption and permeability
  • Improves performance of compounds in lipophilic and hydrophilic formulations
  • A solutions for complex API formulation and development issues
  • Capable of delivering single and combination API formulations
  • Tamper evident

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CONSUMER BENEFITS

  • Full strength efficacy in approximately 30% smaller capsule than traditional softgels
  • Improves compliance, especially for seniors and children
  • Versatile softgel options available in variety of colors, shapes, sizes, and clarity

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CATALENT DEVELOPMENT EXPERTISE

  • Preformulation and feasibility studies
  • Solubility screening of NCEs
  • Softgel capsule fill formulation development
  • Small-scale lab encapsulation for providing early stability data and final formulation selection
  • Shell development
    • An extensive shell library, which enables us to offer a wide variety of options for a range of products
    • A large range of shell gelatin and non-gelatin formula possibilities and compatibility concerns
  • IP (intellectual property) positions including fill formulations for improved bioavailability
  • Extensive technical support in softgel capsule product development
    • Self-emulsifying/micro emulsion vehicle systems
    • Unique formulations potentially leading to patentable line extensions
  • Reliable supply from clinical phases to commercial manufacturing
  • Contingency planning and quality assurance via our large global network

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FACILITIES

All of our sites are subject to annual review so we can remain in compliance with cGMP, FDA, EMA, and locally accredited softgel facilities.